InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: St8sia6

Summary

InnateDB Protein

IDBP-137950.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

St8sia6

Protein Name

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003509

InnateDB Gene

IDBG-137948 (St8sia6)

Protein Structure

UniProt Annotation

Function

Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc- alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups.

Subcellular Localization

Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008373	sialyltransferase activity

Biological Process

GO:0001574	ganglioside biosynthetic process
GO:0006486	protein glycosylation
GO:0006493	protein O-linked glycosylation
GO:0009100	glycoprotein metabolic process
GO:0009247	glycolipid biosynthetic process
GO:0009311	oligosaccharide metabolic process
GO:0016051	carbohydrate biosynthetic process
GO:0097503	sialylation