Version 5.4
Mus musculus Protein: Vnn3
Summary
InnateDB Protein IDBP-138032.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vnn3
Protein Name vanin 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000020190
InnateDB Gene IDBG-138030 (Vnn3)
Protein Structure
UniProt Annotation
Function Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. {ECO:0000269PubMed:11491533}.
Subcellular Localization Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=According to PubMed:11491533, secreted. {ECO:0000269PubMed:11491533}.
Disease Associations
Tissue Specificity Ubiquitous with higher expression in liver. {ECO:0000269PubMed:11491533}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017159 pantetheine hydrolase activity
Biological Process
GO:0006807 nitrogen compound metabolic process
GO:0015939 pantothenate metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID MGI:1347055
InterPro IPR003010 Carbon-nitrogen hydrolase
IPR012101 Biotinidase, eukaryotic
PFAM PF00795
PRINTS
PIRSF PIRSF011861
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZ25
PhosphoSite PhosphoSite-Q9QZ25
TrEMBL
UniProt Splice Variant
Entrez Gene 26464
UniGene Mm.27334
RefSeq NP_036109
MGI ID
MGI Symbol Vnn3
OMIM
CCDS CCDS23734
HPRD
IMGT
EMBL AC153973 AJ132103
GenPept CAB59323

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca