InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: B3gat2

Summary

InnateDB Protein

IDBP-138043.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

B3gat2

Protein Name

beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000066582

InnateDB Gene

IDBG-138041 (B3gat2)

Protein Structure

UniProt Annotation

Function

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in brain, but not in liver and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
GO:0015020	glucuronosyltransferase activity
GO:0046872	metal ion binding

Biological Process

GO:0006486

protein glycosylation

Cellular Component

GO:0000139	Golgi membrane
GO:0005575	cellular_component
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2389490

InterPro

IPR005027 Glycosyl transferase, family 43
IPR029044 Nucleotide-diphospho-sugar transferases

PFAM

PF03360

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P59270

PhosphoSite

PhosphoSite-

TrEMBL

Q5DTT7

UniProt Splice Variant

Entrez Gene

280645

UniGene

Mm.488228

RefSeq

NP_742122

MGI ID

MGI Symbol

B3gat2

OMIM

CCDS

CCDS14850

HPRD

IMGT

EMBL

AB055902 AK048146 AK052640 AK136293 AK220433 BC056368 BC058082

GenPept

AAH56368 AAH58082 BAC20343 BAC33257 BAC35075 BAD90265 BAE22919