Version 5.4
Mus musculus Protein: Sfi1
Summary
InnateDB Protein IDBP-138091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sfi1
Protein Name Sfi1 homolog, spindle assembly associated (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000067261
InnateDB Gene IDBG-138079 (Sfi1)
Protein Structure
UniProt Annotation
Function Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Note=Localized close to the centriole. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019902 phosphatase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005814 centriole
Protein Structure and Domains
PDB ID MGI:1926137
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UZY0
PhosphoSite PhosphoSite-Q3UZY0
TrEMBL A8Y5K4
UniProt Splice Variant
Entrez Gene 78887
UniGene Mm.485866
RefSeq XP_006514960
MGI ID
MGI Symbol Sfi1
OMIM
CCDS
HPRD
IMGT
EMBL AK019095 AK129159 AK133558 AL671968 BC026390 BC046305 BC048950 BC106124 BX572640
GenPept AAH26390 AAH46305 AAH48950 AAI06125 BAB31543 BAC97969 BAE21725 CAI26156 CAI35196

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca