Mus musculus Protein: Taar3
Summary
InnateDB Protein IDBP-138198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Taar3
Protein Name trace amine-associated receptor 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000036817
InnateDB Gene IDBG-138196 (Taar3)
Protein Structure
UniProt Annotation
Function Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the corresponding alcohols, isoamylalcohol and cyclohexanol. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase. {ECO:0000269PubMed:16878137}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Specifically expressed in neurons of the olfactory epithelium. {ECO:0000269PubMed:16878137}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001594 trace-amine receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0008227 G-protein coupled amine receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007606 sensory perception of chemical stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3527427
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR009132 Trace amine associated receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
PFAM PF00001
PF10320
PRINTS PR00237
PR01830
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5QD16
PhosphoSite PhosphoSite-Q5QD16
TrEMBL D8KZH8
UniProt Splice Variant
Entrez Gene 493809
UniGene Mm.379737
RefSeq NP_001008429
MGI ID
MGI Symbol Taar3
OMIM
CCDS CCDS23736
HPRD
IMGT
EMBL AY702327 BC139171 BC139172 FJ372434
GenPept AAI39172 AAI39173 AAV70137 ACP18776