InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cox8a

Summary

InnateDB Protein

IDBP-138387.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cox8a

Protein Name

cytochrome c oxidase, subunit VIIIa

Synonyms

COX8L;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040717

InnateDB Gene

IDBG-138385 (Cox8a)

Protein Structure

UniProt Annotation

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity

Biological Process

GO:1902600

hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:105959

InterPro

IPR003205 Cytochrome c oxidase, subunit 8

PFAM

PF02285

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q64445

PhosphoSite

PhosphoSite-Q64445

TrEMBL

UniProt Splice Variant

Entrez Gene

12868

UniGene

RefSeq

NP_031776

MGI ID

MGI Symbol

Cox8a

OMIM

CCDS

CCDS29521

HPRD

IMGT

EMBL

AK002218 AK002524 AK008594 BC120708 BC120710 U37721

GenPept

AAB38754 AAI20709 AAI20711 BAB21942 BAB22161 BAB25767