InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rcor2

Summary

InnateDB Protein

IDBP-138493.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rcor2

Protein Name

REST corepressor 2

Synonyms

1A13; AW122124; CoREST; Rcor; Rcor1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000063335

InnateDB Gene

IDBG-138489 (Rcor2)

Protein Structure

UniProt Annotation

Function

May act as a component of a corepressor complex that represses transcription. {ECO:0000305}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00512, ECO:0000255PROSITE-ProRule:PRU00624}.

Disease Associations

Tissue Specificity

Predominantly, but not exclusively, expressed in neural tissue. Strongly expressed in neural domains of the developing brain of the developing mouse CNS. {ECO:0000269PubMed:11578870}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003714	transcription corepressor activity
GO:0005515	protein binding