InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Moxd1

Summary

InnateDB Protein

IDBP-138541.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Moxd1

Protein Name

monooxygenase, DBH-like 1

Synonyms

3230402N08Rik; MNCb-5203;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000093460

InnateDB Gene

IDBG-138539 (Moxd1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000269PubMed:15337741}; Single-pass type I membrane protein {ECO:0000269PubMed:15337741}.

Disease Associations

Tissue Specificity

Broadly exprressed, with highest levels in salivary gland and ovary. {ECO:0000269PubMed:15337741}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004497	monooxygenase activity
GO:0005507	copper ion binding
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1921582

InterPro

IPR000323 Copper type II, ascorbate-dependent monooxygenase, N-terminal
IPR000945 Dopamine beta-hydroxylase-related
IPR005018 DOMON domain
IPR008977 PHM/PNGase F domain

PFAM

PF01082
PF03351

PRINTS

PR00767

PIRSF

SMART

SM00664

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt