Version 5.4
Mus musculus Protein: Defa25
Summary
InnateDB Protein IDBP-138563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Defa25
Protein Name defensin, alpha, 25
Synonyms Defcr-2; Defcr2; Defcr25;
Species Mus musculus
Ensembl Protein ENSMUSP00000093075
InnateDB Gene IDBG-705986 (Defa25)
Protein Structure
UniProt Annotation
Function May have microbicidal activities. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006952 defense response
GO:0008150 biological_process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:3630385
InterPro IPR002366 Defensin propeptide
IPR006080 Beta defensin/Neutrophil defensin
IPR006081 Mammalian defensins
IPR016327 Alpha-defensin
PFAM PF00879
PF00323
PRINTS
PIRSF PIRSF001875
SMART SM00048
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5G864
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 13236
UniGene Mm.376982
RefSeq NP_031875
MGI ID
MGI Symbol Defa25
OMIM
CCDS CCDS52502
HPRD
IMGT
EMBL AY746430
GenPept AAW78339

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca