InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Anxa5

Summary

InnateDB Protein

IDBP-138627.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Anxa5

Protein Name

annexin A5

Synonyms

Anx5; R74653;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029266

InnateDB Gene

IDBG-138625 (Anxa5)

Protein Structure

UniProt Annotation

Function

This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding

Biological Process

GO:0007596	blood coagulation
GO:0010033	response to organic substance
GO:0050819	negative regulation of coagulation

Cellular Component

GO:0005622	intracellular
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome
GO:0072563	endothelial microparticle