InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wdr55

Summary

InnateDB Protein

IDBP-138798.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wdr55

Protein Name

WD repeat domain 55

Synonyms

2410080P20Rik; C80692;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039010

InnateDB Gene

IDBG-138796 (Wdr55)

Protein Structure

UniProt Annotation

Function

Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. {ECO:0000269PubMed:18769712}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:18769712}. Cytoplasm {ECO:0000269PubMed:18769712}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006364

rRNA processing

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1915186

InterPro

IPR001680 WD40 repeat
IPR017422 WD repeat protein 55
IPR017986 WD40-repeat-containing domain

PFAM

PF00400

PRINTS

PIRSF

PIRSF038169

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CX97

PhosphoSite

PhosphoSite-Q9CX97

TrEMBL

UniProt Splice Variant

Entrez Gene

67936

UniGene

Mm.271719

RefSeq

NP_080740

MGI ID

MGI Symbol

Wdr55

OMIM

CCDS

CCDS29162

HPRD

IMGT

EMBL

AK018469 AK075958 AK146093 BC131932 BC131934 CH466557

GenPept

AAI31933 AAI31935 BAB31225 BAC36082 BAE26896 EDK97176