Version 5.4
Mus musculus Protein: Sybu
Summary
InnateDB Protein IDBP-138982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sybu
Protein Name syntabulin (syntaxin-interacting)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000087511
InnateDB Gene IDBG-138980 (Sybu)
Protein Structure
UniProt Annotation
Function Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development. {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Colocalizes with syntaxin vesicles along microtubules in neuronal processes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0017075 syntaxin-1 binding
GO:0019894 kinesin binding
Biological Process
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0097433 dense body
Protein Structure and Domains
PDB ID MGI:2442392
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BHS8
PhosphoSite PhosphoSite-Q8BHS8
TrEMBL
UniProt Splice Variant
Entrez Gene 319613
UniGene Mm.410127
RefSeq NP_795972
MGI ID
MGI Symbol Sybu
OMIM
CCDS CCDS37069
HPRD
IMGT
EMBL AB232447 AB232448 AB232449 AK029072 AK030482 AK030720 AK163432 AK220268 BC048945 BC065045
GenPept AAH48945 AAH65045 BAC26277 BAC26984 BAC27098 BAD90193 BAE19961 BAE19962 BAE19963 BAE37345

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca