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InnateDB Protein
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IDBP-139073.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tmem190
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Protein Name
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transmembrane protein 190
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Synonyms
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4930572D21Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000013235
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InnateDB Gene
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IDBG-139071 (Tmem190)
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Protein Structure
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| Function |
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| Subcellular Localization |
Membrane {ECO:0000269PubMed:21273369}; Single-pass type I membrane protein {ECO:0000269PubMed:21273369}. Note=Localizes in the intracellular space in testicular germ cells and sperm. Detected also on the cell surface in post-meiotic round spermatids. In cauda epididymal sperm relocates during the acrosome reaction from the inner-acrosomal membrane onto the equatorial segment surface, on which sperm-oocyte fusion occurs. Colocalizes with IZUMO1 at the inner-acrossomal membrane.
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| Disease Associations |
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| Tissue Specificity |
Detected in testis and in a mixture of spermatogenic cells at various stages (testicular germ cells). Not detected in heart, brain, spleen, lung, liver, skeletal muscle and kidney. {ECO:0000269PubMed:21273369}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
| Accession |
GO Term |
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GO:0043621
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protein self-association
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| Biological Process |
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GO:0002244
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hematopoietic progenitor cell differentiation
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| Cellular Component |
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| PDB ID |
MGI:1925302
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| InterPro |
IPR000519
P-type trefoil
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| PFAM |
PF00088
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| PRINTS |
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| PIRSF |
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| SMART |
SM00018
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9D2E9
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| PhosphoSite |
PhosphoSite-Q9D2E9
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
78052
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| UniGene |
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| RefSeq |
NP_084304
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| MGI ID |
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| MGI Symbol |
Tmem190
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| OMIM |
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| CCDS |
CCDS51976
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| HPRD |
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| IMGT |
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| EMBL |
AK019807
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| GenPept |
BAB31858
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Version 5.4