Mus musculus Protein: Kcnv1 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-139152.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Kcnv1 | ||||||||||
Protein Name | potassium channel, subfamily V, member 1 | ||||||||||
Synonyms | 2700023A03Rik; vibe; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000022967 | ||||||||||
InnateDB Gene | IDBG-139150 (Kcnv1) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity). {ECO:0000250}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:1914748 | ||||||||||
InterPro |
IPR000210
BTB/POZ-like IPR003091 Potassium channel IPR003131 Potassium channel tetramerisation-type BTB domain IPR003968 Potassium channel, voltage dependent, Kv IPR003969 Potassium channel, voltage dependent, Kv6 IPR003970 Potassium channel, voltage dependent, Kv8.1 IPR003971 Potassium channel, voltage dependent, Kv9 IPR003974 Potassium channel, voltage dependent, Kv3 IPR003975 Potassium channel, voltage dependent, Kv4 IPR005821 Ion transport domain IPR011333 BTB/POZ fold IPR013099 Two pore domain potassium channel domain |
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PFAM |
PF02214
PF00520 PF07885 |
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PRINTS |
PR00169
PR01491 PR01492 PR01493 PR01494 PR01498 PR01497 |
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PIRSF | |||||||||||
SMART |
SM00225
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q8BZN2 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 67498 | ||||||||||
UniGene | Mm.404789 | ||||||||||
RefSeq | NP_080476 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Kcnv1 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS27459 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AK012275 AK034091 AK038450 AK076120 AK139482 BC128477 BC128478 | ||||||||||
GenPept | AAI28478 AAI28479 BAB28134 BAC28581 BAC30004 BAC36198 BAE24032 | ||||||||||