Version 5.4
Mus musculus Protein: Defb2
Summary
InnateDB Protein IDBP-139237.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Defb2
Protein Name defensin beta 2
Synonyms BD-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000006745
InnateDB Gene IDBG-139235 (Defb2)
Protein Structure
UniProt Annotation
Function Has bactericidal activity. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Kidney, uterus and to a lesser extent in heart. {ECO:0000269PubMed:9923615}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006952 defense response
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1338754
InterPro IPR001855 Beta defensin type
PFAM PF00711
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P82020
PhosphoSite PhosphoSite-
TrEMBL Q32MH3
UniProt Splice Variant
Entrez Gene 13215
UniGene Mm.41981
RefSeq NP_034160
MGI ID
MGI Symbol Defb2
OMIM
CCDS CCDS40284
HPRD
IMGT
EMBL AJ011800 BC109129 BC109130 CH466580
GenPept AAI09130 AAI09131 CAB42815 EDL32921

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca