Version 5.4
Mus musculus Protein: Mllt10
Summary
InnateDB Protein IDBP-139348.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mllt10
Protein Name myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
Synonyms Af10; B130021D15Rik; D630001B22Rik; mKIAA4140;
Species Mus musculus
Ensembl Protein ENSMUSP00000028076
InnateDB Gene IDBG-139346 (Mllt10)
Protein Structure
UniProt Annotation
Function Probably involved in transcriptional regulation. Binds to cruciform DNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1329038
InterPro IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00628
PRINTS
PIRSF
SMART SM00249
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O54826
PhosphoSite PhosphoSite-O54826
TrEMBL Q8C7B0
UniProt Splice Variant
Entrez Gene 17354
UniGene Mm.209175
RefSeq NP_034934
MGI ID
MGI Symbol Mllt10
OMIM
CCDS CCDS15708
HPRD
IMGT
EMBL AF010135 AK052207 AL928557 AL928589 BC070475 CH466542
GenPept AAD11570 AAH70475 BAC34886 CAM21748 CAM21799 EDL08096 EDL08097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca