InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Moxd2

Summary

InnateDB Protein

IDBP-139469.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Moxd2

Protein Name

monooxygenase, DBH-like 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031937

InnateDB Gene

IDBG-139467 (Moxd2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed at low levels in thymus and testis. {ECO:0000269PubMed:15337741}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004497	monooxygenase activity
GO:0005507	copper ion binding
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2388042

InterPro

IPR000323 Copper type II, ascorbate-dependent monooxygenase, N-terminal
IPR000945 Dopamine beta-hydroxylase-related
IPR005018 DOMON domain
IPR008977 PHM/PNGase F domain

PFAM

PF01082
PF03351

PRINTS

PR00767

PIRSF

SMART

SM00664

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt