Version 5.4
Mus musculus Protein: Slc7a4
Summary
InnateDB Protein IDBP-139507.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc7a4
Protein Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000067243
InnateDB Gene IDBG-139505 (Slc7a4)
Protein Structure
UniProt Annotation
Function Involved in the transport of the cationic amino acids (arginine, lysine and ornithine). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0015171 amino acid transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0008150 biological_process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2146512
InterPro IPR002293 Amino acid/polyamine transporter I
IPR004841 Amino acid permease/ SLC12A domain
PFAM PF13520
PF00324
PRINTS
PIRSF PIRSF006060
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BLQ7
PhosphoSite PhosphoSite-Q8BLQ7
TrEMBL E9Q4Z9
UniProt Splice Variant
Entrez Gene 224022
UniGene Mm.298878
RefSeq XP_006522101
MGI ID
MGI Symbol Slc7a4
OMIM
CCDS CCDS28008
HPRD
IMGT
EMBL AC115733 AK043772 AK162398
GenPept BAC31651 BAE36893

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca