InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CDH10

Summary

InnateDB Protein

IDBP-13957.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CDH10

Protein Name

cadherin 10, type 2 (T2-cadherin)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000264463

InnateDB Gene

IDBG-13953 (CDH10)

Protein Structure

UniProt Annotation

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung. {ECO:0000269PubMed:10386616}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding

Biological Process

GO:0007156	homophilic cell adhesion
GO:0016337	single organismal cell-cell adhesion
GO:0034329	cell junction assembly
GO:0034332	adherens junction organization
GO:0045216	cell-cell junction organization