InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slmap

Summary

InnateDB Protein

IDBP-139878.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slmap

Protein Name

sarcolemma associated protein

Synonyms

D330001L02Rik; mKIAA1601; Slap;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046956

InnateDB Gene

IDBG-139872 (Slmap)

Protein Structure

UniProt Annotation

Function

May play a role during myoblast fusion. {ECO:0000269PubMed:15086317}.

Subcellular Localization

Cell membrane, sarcolemma {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum (By similarity). Detected along the Z- and M-lines in cardiomyocytes (By similarity). {ECO:0000250}.Isoform 1: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner.Isoform 2: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner.

Disease Associations

Tissue Specificity

Expressed in proliferating myoblasts and differentiated myotubes (at protein level). Expressed in myoblasts, cardiac and skeletal muscles. {ECO:0000269PubMed:10986292, ECO:0000269PubMed:15086317}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005615	extracellular space
GO:0005815	microtubule organizing center
GO:0016021	integral component of membrane
GO:0030018	Z disc
GO:0031430	M band
GO:0042383	sarcolemma