InnateDB Protein
|
IDBP-139920.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Tomm7
|
Protein Name
|
translocase of outer mitochondrial membrane 7 homolog (yeast)
|
Synonyms
|
1110020J08Rik; AW047273; Tom7;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000030851
|
InnateDB Gene
|
IDBG-139918 (Tomm7)
|
Protein Structure
|
|
Function |
Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
19 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1913419
|
InterPro |
IPR012621
Mitochondrial import receptor subunit TOM7
|
PFAM |
PF08038
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9D173
|
PhosphoSite |
PhosphoSite-Q9D173
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
66169
|
UniGene |
|
RefSeq |
NP_079670
|
MGI ID |
|
MGI Symbol |
Tomm7
|
OMIM |
|
CCDS |
CCDS39026
|
HPRD |
|
IMGT |
|
EMBL |
AK003864
BC055352
|
GenPept |
AAH55352
BAB23046
|
|
|