Version 5.4
Mus musculus Protein: Spata5
Summary
InnateDB Protein IDBP-140660.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spata5
Protein Name spermatogenesis associated 5
Synonyms 2510048F20Rik; C78064; Spaf;
Species Mus musculus
Ensembl Protein ENSMUSP00000029277
InnateDB Gene IDBG-140658 (Spata5)
Protein Structure
UniProt Annotation
Function May be involved in morphological and functional mitochondrial transformations during spermatogenesis. {ECO:0000269PubMed:10734318}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:10734318}. Mitochondrion {ECO:0000269PubMed:10734318}.
Disease Associations
Tissue Specificity Expressed in testis; with localization to spermatogonia and early spermatocytes in the basal compartment of the seminiferous tubules (at early stages of spermatogenesis). Very weak signals observed in spleen and skin. {ECO:0000269PubMed:10734318}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
Protein Structure and Domains
PDB ID MGI:1927170
InterPro IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR009010 Aspartate decarboxylase-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00004
PF07724
PF13304
PF05496
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q3UMC0
TrEMBL Q8CH38
UniProt Splice Variant
Entrez Gene 57815
UniGene
RefSeq NP_067318
MGI ID
MGI Symbol Spata5
OMIM
CCDS CCDS17321
HPRD
IMGT
EMBL AF453429
GenPept AAN76850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca