InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vdac3

Summary

InnateDB Protein

IDBP-140847.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vdac3

Protein Name

voltage-dependent anion channel 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000009036

InnateDB Gene

IDBG-140845 (Vdac3)

Protein Structure

UniProt Annotation

Function

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane.

Disease Associations

Tissue Specificity

Highest levels of expression detected in testis, less but still abundant expression in heart, kidney, brain, and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0008308	voltage-gated anion channel activity
GO:0015288	porin activity

Biological Process

GO:0001662	behavioral fear response
GO:0006820	anion transport
GO:0007268	synaptic transmission
GO:0007270	neuron-neuron synaptic transmission
GO:0007612	learning
GO:0044070	regulation of anion transport
GO:0055085	transmembrane transport