Version 5.4
Mus musculus Protein: Brms1l
Summary
InnateDB Protein IDBP-141057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brms1l
Protein Name breast cancer metastasis-suppressor 1-like
Synonyms 0710008O11Rik; AI159718; BRMS1; D12Ertd407e;
Species Mus musculus
Ensembl Protein ENSMUSP00000082500
InnateDB Gene IDBG-141055 (Brms1l)
Protein Structure
UniProt Annotation
Function Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
GO:0040008 regulation of growth
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1196337
InterPro IPR013907 Sds3-like
PFAM PF08598
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U1T3
PhosphoSite PhosphoSite-Q3U1T3
TrEMBL
UniProt Splice Variant
Entrez Gene 52592
UniGene Mm.416161
RefSeq NP_001032845
MGI ID
MGI Symbol Brms1l
OMIM
CCDS CCDS36453
HPRD
IMGT
EMBL AK154678 AK155742 BC034885
GenPept AAH34885 BAE32759 BAE33410

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca