InnateDB Protein
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IDBP-141242.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gng3
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Protein Name
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guanine nucleotide binding protein (G protein), gamma 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000093978
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InnateDB Gene
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IDBG-141240 (Gng3)
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Protein Structure
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Abundantly expressed in brain. Low levels in testis.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
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Biological Process |
GO:0006184
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GTP catabolic process
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GO:0007186
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G-protein coupled receptor signaling pathway
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GO:0007204
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positive regulation of cytosolic calcium ion concentration
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Cellular Component |
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PDB ID |
MGI:102704
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InterPro |
IPR001770
G-protein, gamma subunit
IPR015898
G-protein gamma-like domain
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PFAM |
PF00631
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PRINTS |
PR00321
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PIRSF |
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SMART |
SM00224
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TIGRFAMs |
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Modification |
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SwissProt |
P63216
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PhosphoSite |
PhosphoSite-P63216
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14704
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UniGene |
Mm.329700
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RefSeq |
NP_034446
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MGI ID |
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MGI Symbol |
Gng3
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OMIM |
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CCDS |
CCDS29550
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HPRD |
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IMGT |
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EMBL |
AF069953
AK004459
AK032646
BC029680
U38497
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GenPept |
AAB01728
AAC83941
AAH29680
BAB23313
BAC27969
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