Version 5.4
Mus musculus Protein: Arhgef39
Summary
InnateDB Protein IDBP-141259.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgef39
Protein Name RIKEN cDNA E130306D19 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055293
InnateDB Gene IDBG-141257 (Arhgef39)
Protein Structure
UniProt Annotation
Function Promotes cell proliferation. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0030335 positive regulation of cell migration
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:3036286
InterPro IPR000219 Dbl homology (DH) domain
IPR001849 Pleckstrin homology domain
PFAM PF00621
PF00169
PRINTS
PIRSF
SMART SM00325
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q66JY6
PhosphoSite PhosphoSite-Q66JY6
TrEMBL
UniProt Splice Variant
Entrez Gene 230098
UniGene Mm.331567
RefSeq NP_001013395
MGI ID
MGI Symbol Arhgef39
OMIM
CCDS CCDS18098
HPRD
IMGT
EMBL AK163287 AL732506 BC080700
GenPept AAH80700 BAE37276 CAM17181

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca