Version 5.4
Mus musculus Protein: Slc25a21
Summary
InnateDB Protein IDBP-141314.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a21
Protein Name solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039289
InnateDB Gene IDBG-141312 (Slc25a21)
Protein Structure
UniProt Annotation
Function Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006810 transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2445059
InterPro IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BZ09
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 217593
UniGene
RefSeq NP_766165
MGI ID
MGI Symbol Slc25a21
OMIM
CCDS CCDS25925
HPRD
IMGT
EMBL AK036988 AK041694 BC057980
GenPept AAH57980 BAC29659 BAC31036

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca