InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myst3

Summary

InnateDB Protein

IDBP-141416.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myst3

Protein Name

MYST histone acetyltransferase (monocytic leukemia) 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038181

InnateDB Gene

IDBG-141414 (Myst3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0016407	acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0003007	heart morphogenesis
GO:0006334	nucleosome assembly
GO:0006355	regulation of transcription, DNA-templated
GO:0006473	protein acetylation
GO:0016573	histone acetylation
GO:0030099	myeloid cell differentiation
GO:0035019	somatic stem cell maintenance
GO:0035162	embryonic hemopoiesis
GO:0035909	aorta morphogenesis
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043966	histone H3 acetylation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060325	face morphogenesis
GO:0090398	cellular senescence

Cellular Component

GO:0000786	nucleosome
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0016605	PML body
GO:0070776	MOZ/MORF histone acetyltransferase complex

Protein Structure and Domains

PDB ID

MGI:2442415

InterPro

IPR001965 Zinc finger, PHD-type
IPR002717 MOZ/SAS-like protein
IPR005818 Linker histone H1/H5, domain H15
IPR011011 Zinc finger, FYVE/PHD-type
IPR016181 Acyl-CoA N-acyltransferase
IPR019787 Zinc finger, PHD-finger

PFAM

PF01853
PF00538
PF00628

PRINTS

PIRSF

SMART

SM00249
SM00526

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite