Version 5.4
Mus musculus Protein: Tas2r144
Summary
InnateDB Protein IDBP-141456.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tas2r144
Protein Name taste receptor, type 2, member 144
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000067734
InnateDB Gene IDBG-141454 (Tas2r144)
Protein Structure
UniProt Annotation
Function Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008527 taste receptor activity
GO:0033038 bitter taste receptor activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2681312
InterPro IPR007960 Mammalian taste receptor
PFAM PF05296
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TQB8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 387515
UniGene Mm.377922
RefSeq NP_001001453
MGI ID
MGI Symbol Tas2r144
OMIM
CCDS CCDS20062
HPRD
IMGT
EMBL AC155654 AY145468 BK001095
GenPept AAN63043 DAA01234

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca