Version 5.4
Mus musculus Protein: Fpr-rs3
Summary
InnateDB Protein IDBP-141603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fpr-rs3
Protein Name formyl peptide receptor, related sequence 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000071179
InnateDB Gene IDBG-141601 (Fpr-rs3)
Protein Structure
UniProt Annotation
Function May have an olfactory function associated with the identification of pathogens or of pathogenic states. {ECO:0000269PubMed:19387439}.
Subcellular Localization Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed exclusively in vomeronasal neurons (PubMed:19387439 and PubMed:19497865). Expressed in 0.8 % of a subset of sensory neurons located in the apical layer of the vomeronasal organ. Localized in sensory somata as well as dendritic cells. Each neuron appears to express only one receptor gene. {ECO:0000269PubMed:19387439, ECO:0000269PubMed:19497865}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1278318
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88537
PhosphoSite PhosphoSite-O88537
TrEMBL
UniProt Splice Variant
Entrez Gene 14290
UniGene Mm.455334
RefSeq NP_032066
MGI ID
MGI Symbol Fpr-rs3
OMIM
CCDS CCDS49989
HPRD
IMGT
EMBL AC166351 AF071181 BC134352
GenPept AAC34586 AAI34353

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca