Version 5.4
Mus musculus Protein: Gbx1
Summary
InnateDB Protein IDBP-141659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gbx1
Protein Name gastrulation brain homeobox 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000085651
InnateDB Gene IDBG-141657 (Gbx1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity Expressed in CNS including rhombomeres 3 and 5, optic vesicles, and the medial ganglionic eminence. {ECO:0000269PubMed:12799077}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007628 adult walking behavior
GO:0019230 proprioception
GO:0021522 spinal cord motor neuron differentiation
GO:0048663 neuron fate commitment
GO:0097374 sensory neuron axon guidance
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:95667
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P82976
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 231044
UniGene Mm.438109
RefSeq NP_056554
MGI ID
MGI Symbol Gbx1
OMIM
CCDS CCDS19123
HPRD
IMGT
EMBL AF547996 AY319256 M81662
GenPept AAA63311 AAO16238 AAQ19677

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca