InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Asb10

Summary

InnateDB Protein

IDBP-141691.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Asb10

Protein Name

ankyrin repeat and SOCS box-containing 10

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041539

InnateDB Gene

IDBG-141689 (Asb10)

Protein Structure

UniProt Annotation

Function

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0016567	protein ubiquitination
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2152836

InterPro

IPR001496 SOCS protein, C-terminal
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain

PFAM

PF07525
PF00023
PF13606
PF11929
PF12796

PRINTS

PR01415

PIRSF

SMART

SM00253
SM00969
SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91ZT7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

117590

UniGene

Mm.207071

RefSeq

NP_536692

MGI ID

MGI Symbol

Asb10

OMIM

CCDS

CCDS19124

HPRD

IMGT

EMBL

AF398971 AK028538 AK052929 BC141311 BC141313

GenPept

AAI41312 AAI41314 AAK97493 BAC25997 BAC35206