Version 5.4
Mus musculus Protein: Pgrmc2
Summary
InnateDB Protein IDBP-141950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pgrmc2
Protein Name progesterone receptor membrane component 2
Synonyms 4631434O19Rik; 5730409G06Rik; DG6; PMBP;
Species Mus musculus
Ensembl Protein ENSMUSP00000056643
InnateDB Gene IDBG-141948 (Pgrmc2)
Protein Structure
UniProt Annotation
Function Receptor for steroids. {ECO:0000305}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005496 steroid binding
GO:0020037 heme binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1918054
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
PFAM PF00173
PRINTS PR00363
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80UU9
PhosphoSite PhosphoSite-Q80UU9
TrEMBL
UniProt Splice Variant
Entrez Gene 70804
UniGene Mm.490735
RefSeq NP_081834
MGI ID
MGI Symbol Pgrmc2
OMIM
CCDS CCDS50899
HPRD
IMGT
EMBL AC100511 BC044759
GenPept AAH44759

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca