Version 5.4
Mus musculus Protein: Il1f9
Summary
InnateDB Protein IDBP-142169.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il1f9
Protein Name interleukin 1 family, member 9
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000053391
InnateDB Gene IDBG-142167 (Il1f9)
Protein Structure
UniProt Annotation
Function Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0001819 positive regulation of cytokine production
GO:0032755 positive regulation of interleukin-6 production
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:2449929
InterPro IPR000975 Interleukin-1 family
IPR008996 Cytokine, IL-1-like
PFAM PF00340
PRINTS PR00264
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R460
PhosphoSite PhosphoSite-Q3U0P4
TrEMBL Q3U0P4
UniProt Splice Variant
Entrez Gene 215257
UniGene Mm.249379
RefSeq NP_705731
MGI ID
MGI Symbol Il1f9
OMIM
CCDS CCDS50518
HPRD
IMGT
EMBL AK081783 AK156687 AL732430 AY071843 BC116227 BC116228 CH466542
GenPept AAI16228 AAI16229 AAL67153 BAE33808 BAE43375 EDL08162

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca