InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Foxf2

Summary

InnateDB Protein

IDBP-142224.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Foxf2

Protein Name

forkhead box F2

Synonyms

Fkh20; FREAC2; LUN;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046789

InnateDB Gene

IDBG-142222 (Foxf2)

Protein Structure

UniProt Annotation

Function

Probable transcription activator for a number of lung- specific genes. {ECO:0000269PubMed:9676429}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00089}.

Disease Associations

Tissue Specificity

Uniquely expressed in the bronchiolar epithelium and in type II pneumocytes. {ECO:0000269PubMed:9676429}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008134	transcription factor binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030198	extracellular matrix organization
GO:0042249	establishment of planar polarity of embryonic epithelium
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048566	embryonic digestive tract development
GO:0048596	embryonic camera-type eye morphogenesis
GO:0048806	genitalia development
GO:0060021	palate development