Version 5.4
| Mus musculus Protein: Adam18 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-142520.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Adam18 | ||||||||||
| Protein Name | a disintegrin and metallopeptidase domain 18 | ||||||||||
| Synonyms | Adam27; Dtgn3; Tmdc3; tMDCIII; | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000033957 | ||||||||||
| InnateDB Gene | IDBG-142518 (Adam18) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein. | ||||||||||
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Expressed specifically in testis. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:105986 | ||||||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001590 Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF00008
PF01421 PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||||
| SMART |
SM00181
SM00050 SM00608 |
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q9R157 | ||||||||||
| PhosphoSite | PhosphoSite-Q9R157 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 13524 | ||||||||||
| UniGene | Mm.89943 | ||||||||||
| RefSeq | NP_034214 | ||||||||||
| MGI ID | |||||||||||
| MGI Symbol | Adam18 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS22195 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF167405 BC051136 U06148 | ||||||||||
| GenPept | AAA18427 AAD48844 AAH51136 | ||||||||||