Version 5.4
Mus musculus Protein: Hint2
Summary
InnateDB Protein IDBP-142535.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hint2
Protein Name histidine triad nucleotide binding protein 2
Synonyms 1190005L05Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000030192
InnateDB Gene IDBG-142533 (Hint2)
Protein Structure
UniProt Annotation
Function Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006915 apoptotic process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1916167
InterPro IPR001310 Histidine triad (HIT) protein
IPR011146 HIT-like domain
PFAM PF01230
PRINTS PR00332
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D0S9
PhosphoSite PhosphoSite-Q9D0S9
TrEMBL Q5M9J2
UniProt Splice Variant
Entrez Gene 68917
UniGene Mm.25285
RefSeq NP_081147
MGI ID
MGI Symbol Hint2
OMIM
CCDS CCDS18106
HPRD
IMGT
EMBL AF356874 AK004497 AY040765 BC086940 CH466565
GenPept AAH86940 AAK94774 AAM00220 BAB23334 EDL02454

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca