Version 5.4
Homo sapiens Protein: EMP2
Summary
InnateDB Protein IDBP-14266.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EMP2
Protein Name epithelial membrane protein 2
Synonyms NPHS10; XMP;
Species Homo sapiens
Ensembl Protein ENSP00000352540
InnateDB Gene IDBG-237255 (EMP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
Biological Process
GO:0001954 positive regulation of cell-matrix adhesion
GO:0008283 cell proliferation
GO:2001046 positive regulation of integrin-mediated signaling pathway
Cellular Component
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR003933 Epithelial membrane protein EMP-2
IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR004032 PMP-22/EMP/MP20
PFAM PF00822
PF13903
PRINTS PR01455
PR01453
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P54851
PhosphoSite PhosphoSite-P54851
TrEMBL
UniProt Splice Variant
Entrez Gene 2013
UniGene Hs.639113
RefSeq NP_001415
HUGO HGNC:3334
OMIM 602334
CCDS CCDS10541
HPRD 11893
IMGT
EMBL AK313134 AY057060 BC009687 CH471112 U52100 X94770
GenPept AAC51779 AAH09687 AAL27085 BAG35953 CAA64393 EAW85180 EAW85181 EAW85182

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca