InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ascc2

Summary

InnateDB Protein

IDBP-142722.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ascc2

Protein Name

activating signal cointegrator 1 complex subunit 2

Synonyms

1700011I11Rik; 2610034L15Rik; AI482016; ASC1p100; AW046480;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000063272

InnateDB Gene

IDBG-142720 (Ascc2)

Protein Structure

UniProt Annotation

Function

Enhances NF-kappa-B, SRF and AP1 transactivation. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008150	biological_process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1922702

InterPro

IPR003892 Ubiquitin system component Cue
IPR009060 UBA-like

PFAM

PF02845

PRINTS

PIRSF

SMART

SM00546

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91WR3

PhosphoSite

PhosphoSite-Q91WR3

TrEMBL

Q9CVZ2

UniProt Splice Variant

Entrez Gene

75452

UniGene

Mm.439906

RefSeq

NP_083567

MGI ID

MGI Symbol

Ascc2

OMIM

CCDS

CCDS24387

HPRD

IMGT

EMBL

AK005869 AK048876 AK051387 AL606521 BC013537 BC024840

GenPept

AAH13537 AAH24840 BAB24289 BAC33480 BAC34621 CAI35279