InnateDB Protein
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IDBP-143155.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Lamp3
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Protein Name
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lysosomal-associated membrane protein 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000080556
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InnateDB Gene
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IDBG-143153 (Lamp3)
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Protein Structure
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Function |
May play a role in dendritic cell function and in adaptive immunity. {ECO:0000250}.
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Subcellular Localization |
Lysosome membrane {ECO:0000255PROSITE- ProRule:PRU00740}; Single-pass type I membrane protein {ECO:0000255PROSITE-ProRule:PRU00740}. Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000255PROSITE-ProRule:PRU00740}. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2441659
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InterPro |
IPR002000
Lysosome-associated membrane glycoprotein
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PFAM |
PF01299
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PRINTS |
PR00336
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7TST5
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PhosphoSite |
PhosphoSite-Q7TST5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
239739
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UniGene |
Mm.258059
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RefSeq |
NP_796330
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MGI ID |
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MGI Symbol |
Lamp3
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OMIM |
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CCDS |
CCDS37285
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HPRD |
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IMGT |
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EMBL |
AJ510130
AK028039
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GenPept |
BAC25713
CAD52824
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