Version 5.4
| Mus musculus Protein: Cnn1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-143327.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Cnn1 | ||||||||
| Protein Name | calponin 1 | ||||||||
| Synonyms | CN; CnnI; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000001384 | ||||||||
| InnateDB Gene | IDBG-143325 (Cnn1) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Smooth muscle, and tissues containing significant amounts of smooth muscle. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:104979 | ||||||||
| InterPro |
IPR000557
Calponin repeat IPR001715 Calponin homology domain IPR001997 Calponin IPR003096 Smooth muscle protein/calponin |
||||||||
| PFAM |
PF00402
PF00307 |
||||||||
| PRINTS |
PR00889
PR00888 |
||||||||
| PIRSF | |||||||||
| SMART |
SM00033
|
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q08091 | ||||||||
| PhosphoSite | PhosphoSite-Q08091 | ||||||||
| TrEMBL | B2RSH3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 12797 | ||||||||
| UniGene | Mm.456898 | ||||||||
| RefSeq | NP_034052 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Cnn1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22921 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC138863 BC138864 CH466522 L49022 U28932 U38930 U40348 U40349 U40350 U40351 Z19542 | ||||||||
| GenPept | AAB01452 AAB01453 AAC52353 AAC52448 AAI38864 AAI38865 CAA79602 EDL25253 | ||||||||