InnateDB Protein
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IDBP-143422.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mrpl41
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Protein Name
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mitochondrial ribosomal protein L41
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Synonyms
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MRP-L27; Rpml27;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000043561
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InnateDB Gene
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IDBG-143420 (Mrpl41)
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Protein Structure
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Function |
Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003735
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structural constituent of ribosome
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1333816
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InterPro |
IPR019189
Ribosomal protein L27/L41, mitochondrial
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PFAM |
PF09809
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9CQN7
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PhosphoSite |
PhosphoSite-Q9CQN7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
107733
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UniGene |
Mm.23010
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RefSeq |
NP_001026978
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MGI ID |
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MGI Symbol |
Mrpl41
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OMIM |
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CCDS |
CCDS15744
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HPRD |
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IMGT |
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EMBL |
AK003340
AK011837
AK032370
BC034728
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GenPept |
AAH34728
BAB22727
BAB27870
BAC27838
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