Version 5.4
Mus musculus Protein: Fam123c
Summary
InnateDB Protein IDBP-143502.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam123c
Protein Name family with sequence similarity 123, member C
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000054748
InnateDB Gene IDBG-143500 (Fam123c)
Protein Structure
UniProt Annotation
Function Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0008150 biological_process
GO:0016055 Wnt signaling pathway
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:3026939
InterPro IPR019003 Uncharacterised protein family FAM123
PFAM PF09422
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NS69
PhosphoSite PhosphoSite-Q6NS69
TrEMBL
UniProt Splice Variant
Entrez Gene 211383
UniGene Mm.414635
RefSeq NP_998892
MGI ID
MGI Symbol Amer3
OMIM
CCDS CCDS14871
HPRD
IMGT
EMBL AK034979 BC070435
GenPept AAH70435 BAC28901

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca