Version 5.4
Mus musculus Protein: Tacc1
Summary
InnateDB Protein IDBP-143592.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tacc1
Protein Name transforming, acidic coiled-coil containing protein 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000081560
InnateDB Gene IDBG-143588 (Tacc1)
Protein Structure
UniProt Annotation
Function Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosisand colocalizes with AURKC at the midbody during cytokinesis (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019904 protein domain specific binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0022027 interkinetic nuclear migration
GO:0032886 regulation of microtubule-based process
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
Protein Structure and Domains
PDB ID MGI:2443510
InterPro IPR007707 Transforming acidic coiled-coil
PFAM PF05010
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6Y685
PhosphoSite PhosphoSite-Q6Y685
TrEMBL Q3UUD7
UniProt Splice Variant
Entrez Gene 320165
UniGene Mm.456969
RefSeq NP_955355
MGI ID
MGI Symbol Tacc1
OMIM
CCDS CCDS40302
HPRD
IMGT
EMBL AK138513 AY177412 AY177413 BC125389 BC145709
GenPept AAI25390 AAI45710 AAO53447 AAO53448 BAE23690

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca