Version 5.4
Mus musculus Protein: Plekhb2
Summary
InnateDB Protein IDBP-143675.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhb2
Protein Name pleckstrin homology domain containing, family B (evectins) member 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000027297
InnateDB Gene IDBG-143673 (Plekhb2)
Protein Structure
UniProt Annotation
Function Involved in retrograde transport of recycling endosomes. {ECO:0000250}.
Subcellular Localization Recycling endosome membrane {ECO:0000250}; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR. {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in brain, retina, heart and kidney. Detected at lower levels in lung, muscle and nerve. {ECO:0000269PubMed:10200314}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0055038 recycling endosome membrane
Protein Structure and Domains
PDB ID MGI:2385825
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZC7
PhosphoSite PhosphoSite-Q9QZC7
TrEMBL D3Z3L2
UniProt Splice Variant
Entrez Gene 226971
UniGene Mm.475321
RefSeq NP_663491
MGI ID 2DHI
MGI Symbol Plekhb2
OMIM
CCDS CCDS14874
HPRD
IMGT
EMBL AC107738 AF189817 AK039771 AK082118 AK149868 AK150074 AK166091 BC057994
GenPept AAF01332 AAH57994 BAC30448 BAC38413 BAE29136 BAE29285 BAE38565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca