InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mgat2

Summary

InnateDB Protein

IDBP-143882.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mgat2

Protein Name

mannoside acetylglucosaminyltransferase 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057905

InnateDB Gene

IDBG-143880 (Mgat2)

Protein Structure

UniProt Annotation

Function

Catalyzes an essential step in the conversion of oligo- mannose to complex N-glycans. {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
GO:0030246	carbohydrate binding

Biological Process

GO:0006487	protein N-linked glycosylation
GO:0009312	oligosaccharide biosynthetic process
GO:0018279	protein N-linked glycosylation via asparagine

Cellular Component

GO:0000139	Golgi membrane
GO:0005575	cellular_component
GO:0005795	Golgi stack
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2384966

InterPro

IPR007754 N-acetylglucosaminyltransferase II
IPR029044 Nucleotide-diphospho-sugar transferases

PFAM

PF05060

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q921V5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

217664

UniGene

Mm.483133

RefSeq

NP_666147

MGI ID

MGI Symbol

Mgat2

OMIM

CCDS

CCDS25947

HPRD

IMGT

EMBL

AK083370 AK152925 BC010583 BC027169

GenPept

AAH10583 AAH27169 BAC38888 BAE31600