Version 5.4
| Mus musculus Protein: Sqle | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-143962.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sqle | ||||||||
| Protein Name | squalene epoxidase | ||||||||
| Synonyms | AI323792; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000022977 | ||||||||
| InnateDB Gene | IDBG-143960 (Sqle) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. | ||||||||
| Subcellular Localization | Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:109296 | ||||||||
| InterPro |
IPR002938
Monooxygenase, FAD-binding IPR003042 Aromatic-ring hydroxylase-like IPR013698 Squalene epoxidase |
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| PFAM |
PF01494
PF08491 |
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| PRINTS |
PR00420
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P52019 | ||||||||
| PhosphoSite | PhosphoSite-P52019 | ||||||||
| TrEMBL | Q3TQK8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20775 | ||||||||
| UniGene | Mm.296169 | ||||||||
| RefSeq | NP_033296 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Sqle | ||||||||
| OMIM | |||||||||
| CCDS | CCDS27497 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK163502 BC042781 BC056361 CH466545 D42048 | ||||||||
| GenPept | AAH42781 AAH56361 BAA07649 BAE37374 EDL29326 | ||||||||