Mus musculus Protein: Neurl3
Summary
InnateDB Protein IDBP-144049.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neurl3
Protein Name neuralized homolog 3 homolog (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055437
InnateDB Gene IDBG-144047 (Neurl3)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase. Seems to utilize UBE2E1. In vitro, generates polyubiquitin chains via non-canonical lysine residues suggesting that it is not involved in tagging substrates for proteasomal degradation. {ECO:0000269PubMed:15936721}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in alveolar epithelial type II cells. {ECO:0000269PubMed:15936721}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2429944
InterPro IPR001841 Zinc finger, RING-type
IPR006573 NEUZ
PFAM PF13639
PF14634
PF07177
PRINTS
PIRSF
SMART SM00184
SM00588
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CJC5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 214854
UniGene Mm.389110
RefSeq NP_700457
MGI ID
MGI Symbol Neurl3
OMIM
CCDS CCDS14875
HPRD
IMGT
EMBL AF321278 AK040949 AK156207 BC056622
GenPept AAH56622 AAN16205 BAC30757 BAE33626