Version 5.4
Mus musculus Protein: Klhdc2
Summary
InnateDB Protein IDBP-144144.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhdc2
Protein Name kelch domain containing 2
Synonyms 2310022K15Rik; D12Ertd522e; HCLP-1; LCP;
Species Mus musculus
Ensembl Protein ENSMUSP00000021362
InnateDB Gene IDBG-144142 (Klhdc2)
Protein Structure
UniProt Annotation
Function Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1916804
InterPro IPR011498 Kelch repeat type 2
PFAM PF07646
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q4G5Y1
PhosphoSite PhosphoSite-Q4G5Y1
TrEMBL
UniProt Splice Variant
Entrez Gene 69554
UniGene
RefSeq NP_081393
MGI ID
MGI Symbol Klhdc2
OMIM
CCDS CCDS25950
HPRD
IMGT
EMBL AC099934 AK009481 AY513272 BC005581
GenPept AAH05581 AAS82954 BAB26317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca