Version 5.4
| Mus musculus Protein: Spink6 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-144214.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Spink6 | ||||||||
| Protein Name | serine peptidase inhibitor, Kazal type 6 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000069247 | ||||||||
| InnateDB Gene | IDBG-144212 (Spink6) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8 (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Secreted {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:3648654 | ||||||||
| InterPro |
IPR001239
Proteinase inhibitor I1, Kazal metazoa IPR002350 Kazal domain |
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| PFAM |
PF00050
PF07648 |
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| PRINTS |
PR00290
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| PIRSF | |||||||||
| SMART |
SM00280
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BT20 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 433180 | ||||||||
| UniGene | Mm.57302 | ||||||||
| RefSeq | NP_001013819 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Spink6 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29224 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK028032 | ||||||||
| GenPept | BAC25711 | ||||||||